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Long COVID Supplements

Health food supplements including vitamins, minerals, herbal & plant extracts, synbiotics and enzymes, can help treatment and recovery from Long COVID for many people.

READ OUR TOP RECOMMENDATIONS

Guide to the treatment and recovery from Long COVID with supplements

Long COVID (or Long Haul COVID) is a growing concern for many people. It can last for weeks and months, and for some people over a year. There is a growing need to find solutions to this problem.

Considering how important this issue is to tens of thousands of people, we felt that it was worth exploring if supplements (known as health food / herbal / vitamin supplements in the UK or nutraceutical / dietary supplements in the US) could offer an inexpensive and ‘Generally Recognised As Safe’ (GRAS) approach to treat and recover from Long COVID.

The results were mixed:
Some helped significantly however,
Some had no observed effect. 

Thus it was important to choose carefully. 

In this page we present the results of our testing, which shortlisted 16 from a total list of over 100.  

Please read on to find out more, or jump to our top recommendations below.

You may also read our section below “Can supplements really help with medical conditions?” which compares the differences between the UK and German healthcare systems. You might be surprised to find out that in contrast to the UK, German doctors, nurses and pharmacists are trained in and can prescribe herbal supplements.

Content reviewed and updated:

01 December 2021 (GMT)

IMPORTANT NOTICE: This article is designed to be informational but it should not be considered medical advice. If you are currently under medical supervision please always check with your doctor, physician or healthcare professional.

Your needs for Long COVID recovery supplements  

When listening to patients with Long COVID, we found several themes emerging. People we spoke to generally wanted a supplement or supplement stacks (collections of supplements) that would meet the following criteria:

Scientifically Proven
(to be sure it would work)

Fast Acting
(something that worked relatively fast)

Easy to Take
(not have to take dozens of different capsules)

Healthy & Safe
(be good for the body, natural, with no side effects)

Affordable
(reasonably priced)

 Our Top Recommendations: 

RecoverUp Immune Support 24h
[Best All Rounder]

  • Excellent all round supplement for Long COVID treatment & recovery. 
  • 33 different supplement nutrients (vitamin, mineral, plant, herbal, synbiotic and enzymes) combined into a 2 part (AM & PM) set.
  • Reviewed favourably by medical and scientific healthcare professionals (see box below).
  • Supports the body in 10 different ways, including: supporting a normal immune system, normal oxygen transport, normal energy production, normal nervous system and normal psychological functions.
  • Also helps as an antiviral, antioxidant, anti-inflammatory, anticoagulant and immune modulator. Supports gut health and liver detox functions.
  • Patient feedback indicates Long COVID symptoms start to reduce within 2 weeks.
  • Patient feedback increases to 70-75% positive within 4 weeks at double dose.
  • We suggest taking 2 capsules per day of each formula (= double dose) but start with 1 of each if you have a sensitive stomach.
  • Can be taken with Magnesium Bisglycinate, CoQ10 and extra Quercetin if needed.

Click here to learn more

RecoverUp has been recommended by Long COVID patients, healthcare practitioners and our own team (based on personal experience). 

British front-line critical care and functional medicine Doctor Krige gave feedback on RecoverUp, “This has the potential to be an efficient initial option for all those with prolonged COVID-19 symptoms ... I think [it] would be a useful baseline starter for most patients with no safety concerns”. 

Registered Dietitian Dr Mabel Blades stated, “... the nutrients and bioactives which are found in RecoverUp appear to have a possible positive association with the amelioration of the symptoms ... found in long-COVID. While all the items in the supplements can be purchased from various sources it is helpful to have the combination provided."

To read the full quotes from these medical and health care professionals, please see our press release here.

Based on these and other recommendations, we have thus worked with the manufacturers to offer a subsidised price (30% or more off) for those who have Long COVID. Simply click the button below to claim the subsidised price.

GET THE SUBSIDY

Solgar CoQ10 (Coenzyme Q-10) 
[Good for Energy]

  • Great supplement for increasing energy during Long COVID.
  • CoQ10 provides energy to cells (mitochondria) by increasing ATP production and limiting oxidative damage.
  • However for those with Long COVID, dosage should be controlled carefully.
  • Patient feedback indicated 200mg provided noticeable energy improvements
  • Patients indicated 400mg per day was an option if 200mg was tolerated.
  • Some adults under 35 complained of no noticeable effect.
  • CoQ10 works well together with Magnesium Bisglycinate (we suggest 4 capsules per day = approx 100% RDA/NRV).
  • CoQ10 can also be taken optionally with Quercetin or RecoverUp.

Pure Quercetin
[
Good for anti-inflammation]

  • Good herbal nutrient that has various functions helpful for Long COVID.
  • Quercetin can help as an antiviral, anti-inflammatory and anticoagulant.
  • Patient feedback indicates 1000-2000mg tolerated well.
  • Often referred to in stacks for Long COVID by various health practitioners. 
  • Can be taken in place or with EGCG, another potent polyphenol, and both work together in a synergistic manner.
  • Quercetin can be taken to optionally supplement the existing 500mg Quercetin contained per RecoverUp normal dose.
  • Quercetin should be taken in conjunction with the following for maximum benefits: Magnesium Bisglycinate, CoQ10, Zinc, Vitamin D & K2, NAC (N-Acetyl Cysteine), Curcumin and a B-Vitamin Complex.

Can supplements really help with medical conditions?

Supplements have been used for many years to help with various ailments, with usage depending on the country in question. However, do they really work for medical conditions? Let's look at Germany and the UK as a comparison.

Click the read more button below to see the full comparison.

Long COVID treatment & recovery supplements

(Full list of all 16 supplements shortlisted)

Please find below detailed information for each supplement we reviewed. Comments are based on our assessments of published scientific evidence, patient and healthcare practitioners feedback and our own experiences.

Please note the table also includes safety information in the form of Safe Upper Levels (SUL), the No Observed Adverse Effect Level (NOAEL) and Lowest Observed Adverse Effect Level (LOAEL) figures in mg or capsules per day, based on safety data from the UK Department of Health’s report amongst other sources. The amounts suggested are based on an adult weighing 60kg (9.4 stone). As such, your doctor or health professional may recommend more or less dosage based on your body weight.

 Best All Rounder 

RecoverUp Immune Support 24h

Key Core Facts 
£45.00
(Long COVID subdised price)

- 3995mg (actives)
- 120 vegan capsules
- 2 month supply (if 1 capsule each formula per day)
Scientific Evidence
Strong 75%

RecoverUp have thoughtfully combined 33 different vitamin and herbal supplements into this two-part supplement (AM & PM formulas) - which help the body in 10 different ways, including; supporting a normal immune system, normal oxygen transport, normal energy production, normal nervous system and normal psychological functions. It also helps as an antiviral, antioxidant, anti-inflammatory, immune modulator, liver detoxifier and microbiome supporter.
Key Core Facts 
Scientific EvidencePatient Feedback
£45.00
(Long COVID subdised price)

- 3995mg (actives)
- 120 vegan capsules
- 2 month supply (if 1 capsule each formula per day)
Strong 75%

RecoverUp have thoughtfully combined 33 different vitamin and herbal supplements into this two-part supplement (AM & PM formulas) - which help the body in 10 different ways, including; supporting a normal immune system, normal oxygen transport, normal energy production, normal nervous system and normal psychological functions. It also helps as an antiviral, antioxidant, anti-inflammatory, immune modulator, liver detoxifier and microbiome supporter.
Strong 70-75%

Feedback indicates it starts to help reduce Long COVID symptoms for a substantial number of people within two weeks (with noticeable improvements) and with that number rising to 70-75% within 4 weeks at double dose. (We suggest 2 capsules per day of each formula = double dose but start with 1 of each if you have a sensitive stomach).

SUL: 2 capsules per day of each formula
LOAEL: 4 capsules per day of each formula (very safe)
Patient Feedback
Strong 70-75%

Feedback indicates it starts to help reduce Long COVID symptoms for a substantial number of people within two weeks (with noticeable improvements) and with that number rising to 70-75% within 4 weeks at double dose. (We suggest 2 capsules per day of each formula = double dose but start with 1 of each if you have a sensitive stomach).

SUL: 2 capsules per day of each formula
LOAEL: 4 capsules per day of each formula (very safe)

 Good for Energy 

Solgar CoQ10 (Coenzyme Q-10)

Key Core Facts 
£34.99

- 200mg (actives)
- 30 vegan capsules
- 1 month supply (if 1 capsule per day)
Scientific Evidence
Medium to Strong 60-65%

CoQ10 provides energy to cells (mitochondria) by increasing ATP production and limiting oxidative damage. However for those with Long COVID, dosage should be controlled carefully. 
Key Core Facts 
Scientific EvidencePatient Feedback
£34.99

- 200mg (actives)
- 30 vegan capsules
- 1 month supply (if 1 capsule per day)
Medium to Strong 60-65%

CoQ10 provides energy to cells (mitochondria) by increasing ATP production and limiting oxidative damage. However for those with Long COVID, dosage should be controlled carefully. 
Medium to Strong 60-65%

Feedback showed that 200mg per day was enough to provide noticeable and helpful energy level improvements, which are short-term (usually for the day). However for many with Long COVID, considerably higher amounts actually led to (short term) worsening of heart palpitations, which dissipate after reducing the dose.  

SUL: 1200 mg per day
NOAEL (Long COVID): 200mg per day
Patient Feedback
Medium to Strong 60-65%

Feedback showed that 200mg per day was enough to provide noticeable and helpful energy level improvements, which are short-term (usually for the day). However for many with Long COVID, considerably higher amounts actually led to (short term) worsening of heart palpitations, which dissipate after reducing the dose.

SUL: 1200 mg per day
NOAEL (Long COVID): 200mg per day

 Anti-inflammation 

Pure Quercetin

Key Core Facts 
£25.50

250mg (actives)
60 vegetarian capsules
15 days supply (1000mg = 4 capsules per day)
Scientific Evidence
Strong 65%

A polyphenol derived from plants, this has a wide range of biological actions; including antiviral, anti-inflammatory and helps prevent platelet aggregation (prevents blood clotting).  
Key Core Facts 
Scientific EvidencePatient Feedback
£25.50 

- 250mg (actives)
- 60 vegetarian capsules
- 15 days supply (1000mg = 4 capsules per day)
Strong 65%

A polyphenol derived from plants, this has a wide range of biological actions; including antiviral, anti-inflammatory and helps prevent platelet aggregation (prevents blood clotting).  
Medium to Strong 60-65%

Quercetin has become an important herbal supplement for Long COVID. It can be combined with or taken in place of EGCG, another potent polyphenol. These two polyphenols work together in a synergistic manner. 

SUL: 1000mg per day
LOAEL: not established (very safe)
Patient Feedback
Medium to Strong 60-65%

Quercetin has become an important herbal supplement for Long COVID. It can be combined with or taken in place of EGCG, another potent polyphenol. These two polyphenols work together in a synergistic manner. 

SUL: 1000mg per day
LOAEL: not established (very safe)

4. LLS Curcumin

Key Core Facts 
£16.95

- 500mg (actives)
- 60 vegetarian capsules
- 2 months supply (if 1 capsule per day)
Scientific Evidence
Medium to Strong 60-65%

There is growing scientific evidence that cucumin is a natural anti-inflammatory with antioxidant, antiviral, blood-thinning or anticoagulant properties. In particular, there is evidence of endothelial cell protection, which is key to Long COVID recovery. Black pepper (piperine) is required for optimal absorption. 
Key Core Facts 
Scientific EvidencePatient Feedback
£16.95

- 500mg (actives)
- 60 vegetarian capsules
- 2 months supply (if 1 capsule per day)
Medium to Strong 60-65%

There is growing scientific evidence that cucumin is a natural anti-inflammatory with antioxidant, antiviral, blood-thinning or anticoagulant properties. In particular, there is evidence of endothelial cell protection, which is key to Long COVID recovery. Black pepper (piperine) is required for optimal absorption. 
Medium to Strong 60-65%

Feedback for this extract (from Turmeric) is strong. Positive effects are observed in multiple parts of the body. We believe this is due to the nature of Long COVID which is closely related to inflammation of the vascular system (endothelial cells) - ie. the network of veins throughout the body.

SUL: 8000mg per day
LOAEL: not established (very safe)
Patient Feedback
Medium to Strong 60-65%

Feedback for this extract (from Turmeric) is strong. Positive effects are observed in multiple parts of the body. We believe this is due to the nature of Long COVID which is closely related to inflammation of the vascular system (endothelial cells) - ie. the network of veins throughout the body.

SUL: 8000mg per day
LOAEL: not established (very safe)

5. Thorne Zinc Picolinate  

Key Core Facts 
£11.22

- 15mg (actives)
- 60 vegan capsules
- 1 month supply (if 2 capsules per day)
Scientific Evidence
Strong 65%

Zinc is one of the best antiviral minerals we can use. Zinc Picolinate is the best absorbed and most likely to improve blood levels of Zinc over a longer period. (Other forms of Zinc stay in the body for less than 24 hours). 
Key Core Facts 
Scientific EvidencePatient Feedback
£11.22

- 15mg (actives)
- 60 vegan capsules
- 1 month supply (if 2 capsules per day)




Strong 65%

Zinc is one of the best antiviral minerals we can use. Zinc Picolinate is the best absorbed and most likely to improve blood levels of Zinc over a longer period. (Other forms of Zinc stay in the body for less than 24 hours). 



Medium to Strong 60-65%

Emerging evidence indicates that the SARS-CoV-2 virus (or viral particles) can stay in the body after initial infection, ie. during Long COVID. Hence continuing with an antiviral could be necessary. Zinc is best combined with other supplements for increased benefits.

SUL: 25mg per day
LOAEL: 50 mg per day
Patient Feedback
Medium to Strong 60-65%

Emerging evidence indicates that the SARS-CoV-2 virus (or viral particles) can stay in the body after initial infection, ie. during Long COVID. Hence continuing with an antiviral could be necessary. Zinc is best combined with other supplements for increased benefits.

SUL: 25mg per day
LOAEL: 50 mg per day

General Tip: Always start with a lower dose or amount and gradually increase to allow your body to adjust to the new nutrients or vitamins being consumed. 

Scientific References: regarding the terms Safe Upper Levels (SUL) and the No Observed Adverse Effect Level (NOAEL) and Lowest Observed Adverse Effect Level (LOAEL) - Where appropriate, where taken from the ‘Committee on Toxicity (2003) Safe Upper Levels for Vitamins and Minerals. Expert Group on Vitamins and Minerals’. The report is available at GOV.UK: https://cot.food.gov.uk/sites/default/files/vitmin2003.pdf  

Criteria for selecting supplements for Long COVID treatment

Supplements were classed as including vitamins, minerals, amino acids, plant bioactives, enzymes and synbiotics (probiotics and prebiotics). Plant bioactives include herbals and botanicals.

We focused our research for supplements that could be effective for the long term effects (‘Long COVID’) from the recent 2020-2021 outbreak of SARS-CoV-2. We also looked at supplements that could help with recovery from related forms of infection such as SARS, MERS and influenza. We also studied what worked for CFS/ME.

Long COVID recovery supplements: safety

Please note that all of the supplements on this page can generally be taken in conjunction with other medications given by your GP, Physician or healthcare professional, as they are considered equivalent to food in the UK (under Department of Health regulations) or GRAS (Generally Recognised As Safe) in the US (under FDA regulations).  

Supplements Dosage

Please note that dosage is important - and if something is helping your Long COVID symptoms, that doesn’t mean taking more will be helpful. Always start with a small dose and work your way to higher doses gradually, to allow your body time to adjust to the new nutrients / vitamins being consumed. 

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References

Expert Group on Vitamins and Minerals. Safe Upper Levels for Vitamins and Minerals.
https://cot.food.gov.uk/sites/default/files/vitmin2003.pdf

NHS (National Health Service) UK.
https://www.nhs.uk/conditions/vitamins-and-minerals/

The Institute for Functional Medicine.
https://www.ifm.org/

COVID-19 Support Group: Long-Haul COVID.
https://www.wearebodypolitic.com/bodytype/2020/8/16/covid-19-support-group-long-haul

National Library of Medicine.
https://www.nlm.nih.gov/

IMCJ - Integrative Medicine: A Clinician's Journal.
http://www.imjournal.com/

Jon D. Kaiser, MD. Long Haulers Syndrome - An Integrative Approach to Etiology and Treatment.
Integrative Medicine: A Clinician's Journal.
http://www.imjournal.com/abstracts/23042.html

Wachtel-Galor, et al. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.
https://www.ncbi.nlm.nih.gov/books/NBK92773/

Joos et al. Herbal Medicine in Primary Healthcare in Germany: The Patient's Perspective. Evidence-Based Complementary and Alternative Medicine.
https://www.hindawi.com/journals/ecam/2012/294638/

Verhoef, et al. Pharmacogenetic-guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon. British Journal of Clinical Pharmacology.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971980/

Pascoe GmbH. Expertenkreis Naturmedizin: Naturmedizin 2002. Ausbildungssituation an Deutschen Hochschulen (German language).
https://www.pascoe.de/fileadmin/media/pascoe.de/Downloads/Studien/PASCOE_Studie_2002.pdf

Centre for the Promotion of Imports, Netherlands Ministry of Foreign Affairs. What is the demand for natural ingredients for health products on the European market?
https://www.cbi.eu/market-information/natural-ingredients-health-products/what-demand

Read our recommendations again

READ OUR TOP RECOMMENDATIONS